Patrick Mertens

Patrick Mertens

Lyon, France

 

Born in Hasselt (Belgium) 4th November 1958. French nationality, married, 4 children

- Professor of Anatomy

Director of the Department of clinical Anatomy. Claude Bernard University LYON 1

- Neurosurgeon

- Head of the department of Neurosurgery

- Director of the Pain center. Universitary hospital of Neurology and Neurosurgery Pierre WERTHEIMER

 

Education – University appointments:

1987 - Medical Board

1987-1991 - Neurosurgical Residency

1991 - Associate professor of Anatomy.  LYON 1 University

2000 - Neurosciences Ph.D.

2001 - Professor of Anatomy. LYON 1 University

Member of Institute of Neurosciences of LYON

Research Unit INSERM U1028 CNRS UMR 5292 «central integration of pain in human»

 

Fields of interest:

- Functional Neurosurgery (for chronic pain, movement disorders, spasticity, dysfunction of

cranial nerves)

- Research in Neuroanatomy

- Pedagogy for medical sciences

President elected of the French Society of Neurosurgery (since march 2013)

Associate member of the French National Academy of Surgery

206 Publications in peer reviewed journal (reported in Index Medicus/Current Contents/Journal of Citation Reports)

18 chapters in Books

82 invited lectures in international congress - 188 oral / poster presentations in congress

 

Main Publications in peer reviewed journals since last 5 years:

- Subthalamic stimulation in Parkinson's disease: restoring the balance of motivated behaviours. LHOMMÉE E, KLINGER H, THOBOIS S, SCHMITT E, ARDOUIN C, BICHON A, KISTNER A, FRAIX V, XIE J, AYA KOMBO M, CHABARDÈS S, SEIGNEURET E, BENABID AL, MERTENS P, POLO G, CARNICELLA S, QUESADA JL, BOSSON JL, BROUSSOLLE E, POLLAK P, KRACK P.

Brain, 135, 1463-77, 2012

- Treatment of trigeminal neuralgia by radiosurgery. (French)

LATORZEFF I, DEBONO B, SOL JC, MENEGALLI D, MERTENS P, REDON A. Cancer Radiother, 16S, 57-69, 2012

- Improved dexterity after chronic electrical stimulation of the motor cortex for central pain: a special relevance for thalamic syndrome. NUTI C, VASSAL F, MERTENS P, LEMAIRE JJ, MAGNIN M, PEYRON R. Stereotact Funct Neurosurg. 90(6):370-8, 2012

- Anatomical study of the central myelin portion and transitional zone of the vestibulocochlear nerve. GUCLU B, SINDOU M, MEYRONET D, STREICHENBERGER N, SIMON E, MERTENS P. Acta Neurochir. 154(12):2277-83; 2012

- Psychostimulant effect of levodopa: reversing sensitisation is possible. CASTRIOTO A, KISTNER A, KLINGER H, LHOMMEE E, SCHMITT E, FRAIX V, CHABARDES S, MERTENS P, QUESADA JL, BROUSSOLLE E, POLLAK P, THOBOIS SC, KRACK P. J Neurol Neurosurg Psychiatry. 84(1):18-22, 2013

- Definition of a Stereotactic 3-D MRI Template of the Human Insula. AFIF A, BECQ G, MERTENS P. Neurosurgery. [Epub ahead of print], 2013

- Morphometry and localization of the temporal transverse Heschl's gyrus in magnetic resonance imaging: a guide for cortical stimulation of chronic tinnitus. SIMON E, PERROT X, LINNE M, AFIF A, BECQ G, MERTENS P. Surg Radiol Anat. Aug 24. [Epub ahead of print] 2013

- Is the medicolegal issue avoidable in Neurosurgery? A retrospective survey of a series of 115 medicolegal cases from public hospitals. EMERY E, BALOSSIER A, MERTENS P. World Neurosurg. 2013 [Epub ahead of print]

- Neurostimulation for Parkinson’s disease with early motor complications. SCHUEPBACH WM, RAU J, KNUDSEN K, VOLKMANN J, KRACK P, TIMMERMANN L, HÄLBIG TD, HESEKAMP H, NAVARRO SM, MEIER N, FALK D, MEHDORN M, PASCHEN S, MAAROUF M, BARBE MT, FINK

GR, KUPSCH A, GRUBER D, SCHNEIDER GH, SEIGNEURET E, KISTNER A, CHAYNES P, ORY-MAGNE F, BREFEL COURBON C, VESPER J, SCHNITZLER A, WOJTECKI L, HOUETO JL, BATAILLE B, MALTETE D, DAMIER P, RAOUL S, SIXEL-DOERING F, HELLWIG D, GHARABAGHIA, KRÜGER R, PINSKER MO, AMTAGE F, REGIS JM, WITJAS T, THOBOIS S, MERTENS P, KLOSS M, HARTMANN A, OERTEL WH, POST B, SPEELMAN H, AGID Y, SCHADE-BRITTINGER C, DEUSCHL G; EARLYSTIM STUDY GROUP, N Engl J Med; 368:610-22. 2013

- What is the dorsal median sulcus of the spinal cord? Interest for surgical approach of intramedullary tumors. JACQUESSON T, STREICHENBERGERN, SINDOU M, MERTENS P, SIMON E. Surg Radiol Anat, Aug 31, 2013

- Brain opioid receptor density predicts motor cortex stimulation efficacy for chronic pain. MAARRAWI J, PEYRON R, MERTENS P, COSTES N, MAGNIN M, SINDOU M, LAURENT B, GARCIA-LARREA L. Pain;154(11):2563-8, 2013

- Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil. THOBOIS S, LHOMMEE E, KLINGER H, ARDOUIN C, SCHMITT E, BICHON A, KISTNER A, CASTRIOTO A, XIE J, FRAIX V, PELISSIER P, CHABARDES S, MERTENS P, QUESADA JL, BOSSON JL, POLLAK P, BROUSSOLLE E, KRACK P. Brain, 136 :1568-77, 2013

- Motor cortex stimulation does not improve dystonia secondary to a focal basal ganglia lesion. RIEU I, AYA KOMBO M, THOBOIS S, DEROST P, POLLAK P, XIE J, PEREIRA B, VIDAILHET M, BURBAUD P, LEFAUCHEUR JP, LEMAIRE JJ, MERTENS P, CHABARDES S, BROUSSOLLE E, DURIF F.Neurology. Dec 6.2013

- Does the rectus femoris nerve block improve knee recurvatum in adult stroke patients? A kinematic and electromyographic study. GROSS R, DELPORTE L, ARSENAULT L, REVOL P, LEFEVRE M, CLEVENOT D, BOISSON D, MERTENS P, ROSSETTI Y, LUAUTE J. Gait Posture. 2013 Nov

7. [Epub ahead of print]

- Brain opioid receptor density predicts motor cortex stimulation efficacy for chronic pain. MAARRAWI J, PEYRON R, MERTENS P, COSTES N, MAGNIN M, SINDOU M, LAURENT B, GARCIA-LARREA L. Pain. Nov; 154(11):2563-8, 2013

- Comparative cost-effectiveness analysis of sacral anterior root stimulation for rehabilitation of bladder dysfunction in spinal cord injured patients. BENARD A, VERPILLOT E, GRANDOULIER AS, PERROUIN-VERBE B, CHENE G, VIGNES JR; FRENCH STUDY GROUP ON SARS. Neurosurgery. 2013 Oct; [Epub ahead of print]

- Does the rectus femoris nerve block improve knee recurvatum in adult stroke patients? A kinematic and electromyographic study. GROSS R, DELPORTE L, ARSENAULT L, REVOL P, LEFEVRE M, CLEVENOT D, BOISSON D, MERTENS P, ROSSETTI Y, LUAUTE J. Gait Posture. Feb; 39(2):761-6, 2014

- Is pineal melatonin released in the third ventricle in humans? A study in movement disorders. LESTON J, HARTHE C, MOTTOLESE C, MERTENS P, SINDOU M, CLAUSTRAT B. Neurochirurgie. Jun 26. [Epub ahead of print] 2014

- Development of the sensorimotor cortex in the human fetus: a morphological description. AFIF A, TROUILLAS J, MERTENS P. Surg Radiol Anat. Jun 28. [Epub ahead of print] 2014

- Anatomy of the pineal region applied to its surgical approach. SIMON E, AFIF A, M'BAYE M, MERTENS P. Neurochirurgie. May 20 . [Epub ahead of print] 2014

- Is Life better after motor cortex stimulation for pain control? Results at long-term and their prediction by preoperative rTMS. ? ANDRE-OBADIA N, MERTENS P, LELEKOV-BOISSARD T, AFIF A, MAGNIN M, GARCIA-LARREA L. Pain Physician. Jan-Feb;17(1):53-62, 2014

- Is pineal melatonin released in the third ventricle in humans? A study in movement disorders. LESTON J, HARTHE C, MOTTOLESE C, MERTENS P, SINDOU M, CLAUSTRAT B. Neurochirurgie. 2015 Apr-Jun;61(2-3):85-9.

- Development of the sensorimotor cortex in the human fetus: a morphological description. AFIF A, TROUILLAS J, MERTENS P. Surg Radiol Anat. 2015 Mar;37(2):153-60.

- Is Life better after motor cortex stimulation for pain control? Results at long-term and their prediction by preoperative rTMS. ? ANDRE-OBADIA N, MERTENS P, LELEKOV-BOISSARD T, AFIF A, MAGNIN M, GARCIA-LARREA L. Pain Physician. Jan-Feb;17(1):53-62, 2014

- Efficacy of subthalamic nucleus stimulation in C9ORF72 expansion related parkinsonism. DANAILA T, POLO G, KLINGER H, BROUSSOLLE E, MERTENS P, LESAGE S, BRICE A, THOBOIS S. Parkinsonism Relat Disord. 2014 Oct; 20 (10):1104-5

- Anatomical study of muscular latissimus dorsi surface vascularized by the transverse branch of thoraco-dorsal artery. BOUCHER F, PINATEL B, SHIPKOV H, MERTENS P, ROUVIERE O, BRAYE F, MOJALLAL A. Ann Chir Plast Esthet. 2014 Oct; 59(5):327-32

- Anatomy of the pineal region applied to its surgical approach. SIMON E, AFIF A, M'BAYE M, MERTENS P. Neurochirurgie. 2015 Apr-Jun; 61(2-3):70-6

- Neurosurgical treatment of chronic pain. FONTAINE D, BLOND S, MERTENS P, LANTERI-MINET M. Neurochirurgie. 2015 Feb;61(1):22-9

- From "mechanical" to "neuropathic" back pain concept in FBSS patients. A systematic review based on factors leading to the chronification of pain. BLOND S, MERTENS P, DAVID R, ROULAUD M, RIGOARD P. Neurochirurgie. 2015 Mar;61 Suppl 1:S45-56

- Pathophysiological characterisation of back pain generators in failed back surgery syndrome .

RIGOARD P, BLOND S, DAVID R, MERTENS P. Neurochirurgie. 2015 Mar; 61 Suppl 1:S35-44

- Multicolumn spinal cord stimulation for significant low back pain in failed back surgery syndrome: design of a national, multicentre, randomized, controlled health economics trial (ESTIMET Study). ROULAUD M, DURAND-ZALESKI I, INGRAND P, SERRIE A, DIALLO B, PERUZZI P, HIEU PD, VOIRIN J, RAOUL S, PAGE P, FONTAINE D, LANTERI-MINET M, BLOND S, BUISSET N, CUNY E, CADENNE M, CAIRE F, RANOUX D, MERTENS P, NAOUS H, SIMON E, EMERY E, GADAN B, REGIS J, SOL JC, BERAUD G, DEBIAIS F, DURAND G, GUETARNI GING F, PREVOST A, BRANDET C, MONLEZUN O, DELMOTTE A, D'HOUTAUD S, BATAILLE B, RIGOARD P. Neurochirurgie. 2015 Mar;61 Suppl 1:S109-16.

- Anatomy, physiology and neurobiology of the nociception: a focus on low back pain. MERTENS P, BLOND S, DAVID R, RIGOARD P. Neurochirurgie. 2015 Mar;61 Suppl 1:S22-34

- Intraoperative Monitoring of Diaphragm Neural Pathways During Cervical Surgery by Electrical Stimulation and Recordings of Ventilator Waveforms: Physiological Bases and Pilot Study. GEORGOULIS G, PAPAGRIGORIOU E, PARDEY BRACHO GF, MERTENS P, SINDOU M. J Neurosurg Anesthesiol. 2015 Nov 17 [Epub ahead of print]

- Assessment of vinyl polysiloxane as an innovative injection material for the anatomical study of vasculature. DARGAUD J, CHALVET L, DEL CORSO M, CERBONI E, FEUGIER P, MERTENS P, SIMON E. Surg Radiol Anat. 2015 Oct . [Epub ahead of print]

- Postoperative apathy can neutralise benefits in quality of life after subthalamic stimulation for Parkinson's disease. MARTINEZ-FERNANDEZ R, PELISSIER P, QUESADA JL, KLINGER H, LHOMMEE E, SCHMITT E, FRAIX V, CHABARDES S, MERTENS P, CASTRIOTO A, KISTNER A, BROUSSOLLE E, POLLAK P, THOBOIS S, KRACK P. J Neurol Neurosurg Psychiatry. 2016 Mar; 87(3):311-8

- Long-term efficacy and tolerability of bilateral pallidal stimulation to treat tardive dyskinesia. POUCLET-COURTEMANCHE H, ROUAUD T, THOBOIS S, NGUYEN JM, BREFEL-COURBON C, CHEREAU I, CUNY E, DEROST P, EUSEBIO A, GUEHL D, LAURENCIN C, MERTENS P, ORY-MAGNE F, RAOUL S, REGIS J, ULLA M, WITJAS T, BURBAUD P, RASCOL O, DAMIER P. Neurology. 2016 Feb 16; 86(7):651-9.